I love my Sig .45 P220. Expensive to replace parts etc. if that time ever comes but it shoots great. Only paid $250 for it. I think a replacement barrel is 2x that price.
I've shot a S&W 500. Talk about a freaking cannon. I carry the Sig in my car but the 500 is smaller than my Sig. But I wouldnt want to have to shoot either from the inside of my car, I'd probably go deaf